ukadultitpregistry.com

[Ameet Sarpatwari]

ITP Management Guidelines

Freely Available

Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy. Br.J.Haematol. 120 (4):574-596, 2003. http://www.bcshguidelines.com/pdf/BJH574.pdf

J. N. George, S. H. Woolf, G. E. Raskob, J. S. Wasser, L. M. Aledort, P. J. Ballem, V. S. Blanchette, J. B. Bussel, D. B. Cines, J. G. Kelton, A. E. Lichtin, R. McMillan, J. A. Okerbloom, D. H. Regan, and I. Warrier. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood 88 (1):3-40, 1996.
http://bloodjournal.hematologylibrary.org/cgi/reprint/88/1/3

ITP Reviews

Adult ITP

Freely Available

R. Stasi and D. Provan. Management of immune thrombocytopenic purpura in adults. Mayo Clin. Proc. 79 (4):504-522, 2004.
www.mayoclinicproceedings.com/pdf%2F7904%2F7904r.pdf

Paid Subscription Required

D. Provan and A. Newland. Fifty years of idiopathic thrombocytopenic purpura (ITP): management of refractory itp in adults. Br.J.Haematol. 118 (4):933-944, 2002.

D. Provan and A. Newland. Idiopathic thrombocytopenic purpura in adults. J.Pediatr.Hematol.Oncol. 25 Suppl 1:S34-S38, 2003.

Paediatric ITP

Freely Available

D. J. Nugent. Immune thrombocytopenic purpura of childhood. Hematology.Am.Soc.Hematol.Educ.Program.:97-103, 2006.
http://asheducationbook.hematologylibrary.org/cgi/reprint/2006/1/97

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M. D. Tarantino and P. H. Bolton-Maggs. Update on the management of immune thrombocytopenic purpura in children. Curr.Opin.Hematol. 14 (5):526-534, 2007.

ITP in Pregnancy

Freely Available

K. E. Webert, R. Mittal, C. Sigouin, N. M. Heddle, and J. G. Kelton. A retrospective 11-year analysis of obstetric patients with idiopathic thrombocytopenic purpura. Blood 102 (13):4306-4311, 2003.
http://bloodjournal.hematologylibrary.org/cgi/reprint/102/13/4306

Paid Subscription Required

T. Gernsheimer and K. R. McCrae. Immune thrombocytopenic purpura in pregnancy. Curr.Opin.Hematol. 14 (5):574-580, 2007.

Population-Based Epidemiological Studies of ITP

Freely Available

H. Frederiksen and K. Schmidt. The incidence of idiopathic thrombocytopenic purpura in adults increases with age. Blood 94 (3):909-913, 1999.
http://bloodjournal.hematologylibrary.org/cgi/reprint/94/3/909

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A. J. Neylon, P. W. Saunders, M. R. Howard, S. J. Proctor, and P. R. Taylor. Clinically significant newly presenting autoimmune thrombocytopenic purpura in adults: a prospective study of a population-based cohort of 245 patients. Br.J.Haematol. 122 (6):966-974, 2003.

J. B. Segal and N. R. Powe. Prevalence of immune thrombocytopenia: analyses of administrative data. J.Thromb.Haemost. 4 (11):2377-2383, 2006.

Pre-Splenectomy Platelet-Labeled Indium Scanning

Freely Available

F. Radaelli, P. Faccini, M. Goldaniga, E. Guggiari, E. Pozzoli, A. T. Maiolo, A. Ciani, and E. M. Pogliani. Factors predicting response to splenectomy in adult patients with idiopathic thrombocytopenic purpura. Haematologica 85 (10):1040-1044, 2000.
http://www.haematologica.org/cgi/reprint/85/10/1040

Paid Subscription Required

Y. Najean, J. D. Rain, and C. Billotey. The site of destruction of autologous 111In-labelled platelets and the efficiency of splenectomy in children and adults with idiopathic thrombocytopenic purpura: a study of 578 patients with 268 splenectomies. Br.J.Haematol. 97 (3):547-550, 1997.

Y. Najean, V. Dufour, J. D. Rain, and M. E. Toubert. The site of platelet destruction in thrombocytopenic purpura as a predictive index of the efficacy of splenectomy. Br.J.Haematol. 79 (2):271-276, 1991.

Long-Term Outcome of Splenectomy in ITP

Freely Available

K. Kojouri, S. K. Vesely, D. R. Terrell, and J. N. George. Splenectomy for adult patients with idiopathic thrombocytopenic purpura: a systematic review to assess long-term platelet count responses, prediction of response, and surgical complications. Blood 104 (9):2623-2634, 2004.
http://bloodjournal.hematologylibrary.org/cgi/reprint/104/9/2623

Helicobacter pylori Eradication ITP

Freely Available

R. Sato, K. Murakami, K. Watanabe, T. Okimoto, H. Miyajima, M. Ogata, E. Ohtsuka, M. Kodama, Y. Saburi, T. Fujioka, and M. Nasu. Effect of Helicobacter pylori eradication on platelet recovery in patients with chronic idiopathic thrombocytopenic purpura. Arch.Intern.Med. 164 (17):1904-1907, 2004.
http://archinte.ama-assn.org/cgi/reprint/164/17/1904

Paid Subscription Required

M. Kuwana and Y. Ikeda. Helicobacter pylori and immune thrombocytopenic purpura: unsolved questions and controversies. Int.J.Hematol. 84 (4):309-315, 2006.
R. Stasi, Z. Rossi, E. Stipa, S. Amadori, A. C. Newland, and D. Provan. Helicobacter pylori eradication in the management of patients with idiopathic thrombocytopenic purpura. Am.J.Med. 118 (4):414-419, 2005.

Eltrombopag/Promacta Treatment in ITP

Freely Available

D. J. Kuter. New thrombopoietic growth factors. Blood 109 (11):4607-4616, 2007.
http://bloodjournal.hematologylibrary.org/cgi/reprint/109/11/4607

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J. B. Bussel, G. Cheng, M. N. Saleh, B. Psaila, L. Kovaleva, B. Meddeb, J. Kloczko, H. Hassani, B. Mayer, N. L. Stone, M. Arning, D. Provan, and J. M. Jenkins. Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura. N.Engl.J.Med. 357 (22):2237-2247, 2007.

AMG531/Romiplostin Treatment in ITP

Freely Available

J. B. Bussel, D. J. Kuter, J. N. George, R. McMillan, L. M. Aledort, G. T. Conklin, A. E. Lichtin, R. M. Lyons, J. Nieva, J. S. Wasser, I. Wiznitzer, R. Kelly, C. F. Chen, and J. L. Nichol. AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP. N.Engl.J.Med. 355 (16):1672-1681, 2006.
http://content.nejm.org/cgi/content/full/355/16/1672

D. J. Kuter. New thrombopoietic growth factors. Blood 109 (11):4607-4616, 2007.
http://bloodjournal.hematologylibrary.org/cgi/reprint/109/11/4607

Paid Subscription Required

D. J. Kuter, J. B. Bussel, R. M. Lyons, V. Pullarkat, T. B. Gernsheimer, F. M. Senecal, L. M. Aledort, J. N. George, C. M. Kessler, M. A. Sanz, H. A. Liebman, F. T. Slovick, J. T. de Wolf, E. Bourgeois, T. H. Guthrie, Jr., A. Newland, J. S. Wasser, S. I. Hamburg, C. Grande, F. Lefrere, A. E. Lichtin, M. D. Tarantino, H. R. Terebelo, J. F. Viallard, F. J. Cuevas, R. S. Go, D. H. Henry, R. L. Redner, L. Rice, M. R. Schipperus, D. M. Guo, and J. L. Nichol. Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial. Lancet 371 (9610):395-403, 2008.

Anti-D Treatment in ITP

Freely Available

N. Cooper, B. M. Woloski, E. M. Fodero, M. Novoa, M. Leber, J. H. Beer, and J. B. Bussel. Does treatment with intermittent infusions of intravenous anti-D allow a proportion of adults with recently diagnosed immune thrombocytopenic purpura to avoid splenectomy? Blood 99 (6):1922-1927, 2002.
http://bloodjournal.hematologylibrary.org/cgi/reprint/99/6/1922

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J. W. Semple, D. Allen, M. Rutherford, M. Woloski, M. David, C. Wakefield, S. Butchart, J. Freedman, and V. Blanchette. Anti-D (WinRho SD) treatment of children with chronic autoimmune thrombocytopenic purpura stimulates transient cytokine/chemokine production. Am.J.Hematol. 69 (3):225-227, 2002.

Rituximab Treatment in ITP

Freely Available

D. Provan, T. Butler, M. L. Evangelista, S. Amadori, A. C. Newland, and R. Stasi. Activity and safety profile of low-dose rituximab for the treatment of autoimmune cytopenias in adults. Haematologica 92 (12):1695-1698, 2007.
http://www.haematologica.org/cgi/reprint/92/12/1695

F. Zaja, M. L. Battista, M. T. Pirrotta, S. Palmieri, M. Montagna, N. Vianelli, L. Marin, M. Cavallin, M. Bocchia, M. Defina, M. Ippoliti, F. Ferrara, F. Patriarca, M. A. Avanzini, M. Regazzi, M. Baccarani, M. Isola, F. Soldano, and R. Fanin. Lower dose rituximab is active in adults patients with idiopathic thrombocytopenic purpura. Haematologica, 2008.
http://www.haematologica.org/cgi/reprint/haematol.12206v1

Inherited Thrombocytopenias

Freely Available

J. G. Drachman. Inherited thrombocytopenia: when a low platelet count does not mean ITP. Blood 103 (2):390-398, 2004. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14504084

C. L. Balduini, M. Cattaneo, F. Fabris, P. Gresele, A. Iolascon, F. M. Pulcinelli, and A. Savoia. Inherited thrombocytopenias: a proposed diagnostic algorithm from the Italian Gruppo di Studio delle Piastrine. Haematologica 88 (5):582-592, 2003.
http://www.haematologica.org/cgi/reprint/87/8/860

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I. M. Morison, E. M. Cramer Borde, E. J. Cheesman, P. L. Cheong, A. J. Holyoake, S. Fichelson, R. J. Weeks, A. Lo, S. M. Davies, S. M. Wilbanks, R. D. Fagerlund, M. W. Ludgate, F. M. da Silva Tatley, M. S. Coker, N. A. Bockett, G. Hughes, D. A. Pippig, M. P. Smith, C. Capron, and E. C. Ledgerwood. A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia. Nat.Genet. 40 (4):387-389, 2008.